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In this high-stakes contest, bioavailability is the ultimate challenge, determining how much of a drug or nutrient reaches its target to work its magic

[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Radford-Smith D.E., Yates A.G., Rizvi L., Anthony D.C., Probert F

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252 Additionally, nitric oxide (NO) induces HIF1 expression by S-nitrosylating Cys800 or Cys520, preventing its binding to the Von HippelLindau (VHL) protein and proteasomal degradation
