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In the first reaction, bisphosphoglycerate mutase acts as a synthase, catalyzing the isomerization of 1,3-BPG to 2,3-bisphosphoglycerate

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Of these, 184 studies were excluded due to the presence of irrelevant or single-arm results, leaving a total of 10 articles for inclusion in the meta-analysis

Of all tested compounds, we were only able to identify ligand density of heme bound within the TMH domain (Extended Data Fig

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