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The introduction of this term was met with criticism from parts of the professional community, who expressed concern that the new nomenclature might obscure clinically important differences in the pathophysiology and natural history of liver injury between metabolic and alcoholic etiologies

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CrAT uses short-chain acyl groups (C1-C4) as substrate, whereas COT uses both medium and long-chain fatty acids (C5-C12) having a preference for medium chain acyl-CoA

The interactions between PD-L1 and PD-1 normally help prevent immune-mediated tissue damage upon activation

J Polymers