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Furthermore, mutations in that abolish KEAP1 function were also found to activate NRF2 and promote the growth of lung cancer cells [96]

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Loss of acetoacetate coenzyme A transferase activity in tumours of peripheral tissues

doi: 10.3389/fpsyt.2022.1037588

This is perplexing as TREM2 (generally known to be key to A clearance
