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and van der Poll T., Coagulation and Sepsis, Thrombosis Research 149 (2017): 3844

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TIGAR can aggravate myocardial ischemia injury and heart failure in animal and cell models (Kimata et al., 2010
85 Moreover, the phagocytic activity of macrophages and monocytes significantly decreases during aging, leading to the accumulation of unphagocytosed debris, chronic sterile inflammation, and the exacerbation of tissue aging and damage
