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Journal of Endocrinology and Metabolism (2013) 3

Pharmacological treatment of the over-weight patient

Most patients report a noticeable energy lift within 24 to 72 hours of a B12 shot, with peak effects around day 1 to 3 post-injection

These injections typically contain hydroxocobalamin or cyanocobalamin, with hydroxocobalamin being the preferred formulation in the UK as it is retained in the body for longer periods
