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POAG has a clear genetic foundation, with heritability amongst twins ~0.95, and siblings of affected individuals having nearly an eight-fold increase risk of developing the disease

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doi: 10.1016/j.jmb.2006.05.056

We then used Fishers r -to- z transformation to test the significance of difference between the correlations, and found that the correlation between glutamate and GSH was significantly weaker in patients compared to the healthy control subjects ( Z = 2.26, p = 0.023) (see Fig

Furthermore, apoptosis is regulated by two main pathways, the death receptor pathway and the mitochondrial pathway, with ROS strongly implicated in the signal transduction of these pathways (Johar et al., 2015)