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A deficiency in zinc or defects in pyridoxal kinase can lead to seizure disorders, particularly in seizure-prone pre-eclamptic patients (hypertensive condition in late pregnancy)
[DOI] [PMC free article] [PubMed] [Google Scholar] Pawlak 2013 Pawlak R, Parrott SJ, Raj S, CullumDugan D, Lucus D

Tesaglitazar treatment did not change Ppargc1a and SIRT1 expression in Ppara / mice
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