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Description
The Process: Alcohol Intake and the Liver Alcohol enters the body
Namely, redox-active metals, like Fe 2+ , react with peroxides generating highly active hydroxyl radicals (R-HO ) that further propagate the peroxidation reaction ( Cysteine, Lipid Peroxides and Ferroptosis Glutathione-Dependent Ferroptosis Since characterization of ferroptosis in 2012, the cysteine-GSH-GPx4 axis is described as essential pathway for its regulation, and thus seen as potential therapeutic target
(2020) 9:E55513
10.1096/fj.11-186460 FASEB J
The study concerned men in whom the sperm quality was poor due to unilateral varicocele or germ-free genital tract inflammation -two conditions in which ROS or other toxic compounds are indicated as causative factors
