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7 Conclusions and discussion 7.1 Integrated mechanisms of the microbiota-gut-brain-immune axis in schizophrenia By integrating the evidence discussed throughout this review, we propose a comprehensive model illustrating the MGB-immune interactions in schizophrenia (See Figure 3 )

415 The potential mechanism underlying this synergy is that D-pen upregulates the copper transport proteins hCtr1 and ATP7A, which share a transport system with platinum, 416 thereby increasing intracellular platinum levels

The concentration of the NADPH product was calculated by constructing a standard curve of NADPH

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P589 the effects of vanillic acid on production of testosterone and function of insulin in adipose and ovarian tissues in rat model of polycyctic ovary syndrome