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Clinical literature references loading phases, maintenance phases, and cycle durations that vary by provider and patient profile

however, this phenomenon is accompanied by a continuous release of glutamate and substance P onto the second-order neurons, alongside diminished central levels of opioid peptides and serotonin [139,140]
Possibly relevant to case 4 is that at least in mice, ibuprofen doses of 1.0 mg/kg or more raise VEGF levels [53]

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