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Induction of Gpx4-deficient macrophages with IL-4, which triggers M2 macrophage activation, severely disrupted the cellular redox balance and led to ferroptosis

To summarize, we demonstrate the detrimental effect of exogenous antioxidant thiols on the C

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Similar results have been reported by some other studies ( Reference Dutta, Rivlin and Pinto 24 , Reference Horiuchi, Hirano and Ono 25 )