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[DOI] [PMC free article] [PubMed] [Google Scholar] 8.Ayloo S, Lazo CG, Sun S, Zhang W, Cui B, Gu C

Lakkakorpi, P

CAF-activated interleukin 6/8 (IL-6/8)/JAK pathway has been related to the stabilization of bromodomain and extra-terminal protein family member 4 (BRD4), resulting in the resistance to bromodomain and extra-terminal motif (BET) inhibitors (Wang et al., 2021b)

In osteoarthritis, fisetin also suppressed IL-1-induced production of TNF-, IL-6, COX-2, iNOS, MMP-3, MMP-13, and ADAMTS-5 via activation of SIRT1 [69,70]

These results suggested that DNA damage significantly promoted the nuclear translocation of RanBPM protein through ATM-dependent pathways