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Johansen, P., von Moos, S., Mohanan, D., Kndig, T

It is approved for use in CF patients with two copies of the Phe508del (formerly F508del) CFTR mutation who are aged 6 years and older

10.1002/glia.22731 16 GrgB.SchliessF.HussingerD

The intranasal GHK-Cu treatment was found to delay cognitive impairment, reduce amyloid plaques, and lower inflammation levels in the frontal cortex and hippocampus .37 Randomized controlled trials in human patients are needed to confirm the benefit of GHK-Cu for cognitive decline and Alzheimers disease as well as to evaluate safe and effective human dosing (the human dose equivalent of 15mg/kg in mice would be ~1.2mg/kg, though data on this or any other dosing nasally in humans is not currently available), but preliminary animal trials are promising

Garca-Silva, Extracellular vesicles and melanoma: new perspectives on tumor microenvironment and metastasis