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Not surprisingly, mobilization of free fatty acids from the adipose tissue is directly proportional to hepatic ketogenesis (Fougerat et al., 2021)

Nat Struct Mol Biol 13(12):11351140 Wen W, Yan J, Zhang M (2006) Structural characterization of the split pleckstrin homology domain in phospholipase C-gamma1 and its interaction with TRPC3

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Recent studies, however, have shown that high levels of circulating TMAO may exacerbate DKD, suggesting that choline-TMA lyase inhibitors (such as DMB, IMC) might have potential in improving DKD ( Dioscorea polystachya Turcz., Coptis chinensis, Achyranthes bidentata Blume, Leonurus japonicus Houtt, Rehmannia glutinosa, Cornus officinalis, and Zea mays L

A role for autophagy in the extension of lifespan by dietary restriction in C