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Funding This work was financially supported by the National Natural Science Foundation of China (82373955), the Natural Science Foundation from Guangdong Science and Technology Department of China (2023A1515012633), the Science and Technology Program of Guangzhou (202201011600) and the Dean's Fund (YQ202302)

Loss of furin due to viral pre-utilization may result in increased growth, invasiveness and cytokine production in the bone-joint synovium and aggravate rheumatoid arthritis 350