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Description
Pernicious anemia: Autoimmune destruction of gastric parietal cells, leading to decreased intrinsic factor production, essential for B12 absorption

There's a lot of chatter, but not a lot of solid info
Colca 2D / 1N program
Therefore, there is a very low risk of B12 toxicity, even at high doses like 1,000 mcg a day

The preclinical literature does not prominently describe heart rate elevation
