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[ Links ] Bymaster FP, Zhang W, Carter PA, Shaw J, Chernet E, Phebus L, Wong DT, Perry KW (2002) Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex
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An enzyme called tyrosinase is needed to create melanin (the pigment that causes the brown spots) and while several other skin lightening agents work to inhibit the synthesis of tyrosinase itself (like vitamin C or licorice), arbutin lets tyrosinase be and rather hinders the melanin-forming activity of the enzyme
