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Functional consequences of the disruption of -globin-eNOS binding via an -globin mimetic peptide have been observed ex vivo, by increased NO sensitivity of isolated small arteries from mice and humans (124, 166), and in vivo, in lowering of systemic blood pressure in mice (164)

CSE is a highly inducible protein and can be regulated by several factors depending on the cell type and tissue (Figure 2C)

Kreindler TG

Hryniewicz MM, Kredich NM (1991) The cysP promoter of Salmonella typhimurium : characterization of two binding sites for CysB protein, studies of in vivo transcription initiation, and demonstration of the anti-inducer effects of thiosulfate

Impaired inflammasome activation and bacterial clearance in G6PD deficiency due to defective NOX/p38 MAPK/AP-1 redox signaling