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Ferroptosis is an iron-dependent, non-apoptotic form of cell death characterized by lipid peroxidation-driven loss of plasma membrane integrity, primarily mediated through three interconnected mechanisms: iron metabolism dysregulation, glutathione peroxidase 4 (GPX4) inactivation with concomitant glutathione depletion, and lipoxygenase (LOX)-catalyzed lipid peroxidation

Unnoticed lesions and incorrect delineations can lead to tumor recurrence or iatrogenic tissue damage

Organic combination of the IVD and stem cell technology has outstanding advantages for IDD treatment and recovery, but remains controversial [10,11,12]

J., Han, E., Kim, S.-J., Zhang, L., Koob, G

The small molecule inhibitors or gene silencing of GLS1 expression has shown antitumor activity in a variety of cancers, including melanoma (Varghese et al., 2021), breast cancer (Gross et al., 2014), pancreatic cancer (Son et al., 2013), acute myeloid leukemia (Emadi et al., 2014), and malignant glioma (Yamashita et al., 2021)