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doi:10.2165/11599200-00000000000000 [DOI] [PMC free article] [PubMed] [Google Scholar] 20.Xu Q, Pan J, Yu J, et al

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Each fragment has ~500 overlapping residues with the neighboring fragments

found that TMAO promoted calcium/phosphate-induced calcification in the vascular smooth muscle cells of rats and human urinary system patients in a dose-dependent manner, and upregulated the expression of bone-related molecules (Runt-related transcription factor2, Runx2, and Bone morphogenetic protein-2, BMP2)