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ERK, extracellular regulated kinase
Na reviso mais recente e de melhor qualidade metodolgica, 14 cinco estudos foram includos com 1.587, participantes e a metanlise resultou em sensibilidade de 89,4% (IC 95%: 83,2 a 93,5%) e especificidade de 60,3% (IC 95%: 50,9 a 69%), tambm com heterogeneidade importante nas anlises
Although cell therapies with BMSCs are considered safe, it can cause serious adverse effects like hyperthermia and malignant hypertension which requires further investigation [109]
Several strategies help restore the hypoactive GABAergic tone by acting through diverse mechanisms and hence providing a more fundamental understanding to target GABA-associated CNP (Fig
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