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K.ParkJ
Apart from its role in DNA methylation, folate exhibits antioxidant properties that have been found to regulate the proliferation of cancer cells through three main mechanisms: (i) enhances the coupling of eNOS to cofactor tetrahydrobiopterin (BH4), hence inhibiting the formation of superoxide anion and the resulting peroxynitrite, a potent oxidant involved in various pathological conditions
Supplementation with Folic Acid or 5-Methyltetrahydrofolate and Prevention of Neural Tube Defects: An Evidence-Based Narrative Review
Clement F, Martin A, Venara M, de Lujan Calcagno M, Matho C, Maglio S, et al
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