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The most classic findings of PSC include large bile ducts surrounded by concentric fibrosis, which is also referred to as onion skin fibrosis ( Figure 7 )

In a previous study, high concentrations of iron and cadmium increased oxidative stress in the seminal plasma and sperm homogenate of the infertile group, decreased the content of antioxidants, and thus had a strong toxic effect on spermatogenesis by producing excessive oxidants and inducing apoptosis (14)

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Once the crisis is over, B12 levels eventually return to normal

Under 90 dB SPL noise exposure, most microglia in both Nrf2-KO mice and control WT mice exposed to pseudo-noise displayed a typical, branched morphology