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When Rose proposed these amounts he suggested that a "safe intake" should be twice that amount or 2.0 g/day, probably acknowledging that his studies had been done on limited numbers of individuals, usually 36 for each amino acid
The global prevalence of glucose-6-phosphate dehydrogenase deficiency: A systematic review and meta-analysis
E., Gange, R
In other words, without CoQ10, there is no synthesis of ATP and therefore a defective mitochondrion
Toxicology 186 , 159170 (2003)
