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2ce), indicating that either DEG treatment for 6 h is insufficient to modify the OGDHc-E2, or that exogenous glutarate preferentially alters the PDHc, as previously reported 9
Kommaddi et al., 2015
Current medications provide symptom relief rather than exerting disease-modifying effect
While not aimed at persister states, such resistance-focused adaptive strategies underscore a broader shift toward dynamic treatment modulation in response to tumor evolution
