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The importance of intracellular targeting of cortactin has been shown with a cell-permeable peptide that binds cortactin, and inhibits the invasion of a range of cancers including glioblastomas (Hashimoto et al., 2006)

doi: 10.1016/j.envint.2018.07.029

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Key safety considerations: GLP-1 agonists are contraindicated in personal or family history of medullary thyroid carcinoma, MEN2 syndrome, or pancreatitis