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Dihexa works by binding to the HGF receptor c-Met on hippocampal neurons, activating intracellular signaling pathways that increase synaptogenesis, dendritic spine density, and NMDA receptor expression

Under a pharmacological point of view, Glutaminase represents an important target for anticancer therapy (82)

It was designed as a modified version of the C-terminal portion of human growth hormone (hGH)

[DOI] [PubMed] [Google Scholar] 60.Dinkova-Kostova A.T., Kostov R.V., Canning P

One major consequence of metal/metalloid toxicity is the excess generation of ROS and subsequent oxidative stress (Hasanuzzaman and Fujita 2013)