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The effects of low-dose methotrexate on thymidylate synthetase activity in human peripheral blood mononuclear cells

Preterm Birth and Low Birth Weight Preterm birth (PTB), defined as delivery before 37 weeks of gestation, may be associated with HHcy and MTHFR polymorphisms [115]
The transition metal complex could also catalyze the cyclization inside cancer cells
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This bidirectional behavior highlights a critical context dependence in antioxidant biology, where the same metabolite may either suppress or amplify ferroptotic stress depending on iron availability and intracellular redox flux
