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This study not only elucidates the mechanisms of PARP1-mediated PXR E194 ribosylation in AILI but also identifies Sch B as the first specific inhibitor of this pathway, providing a theoretical basis for precision detoxification strategies targeting posttranslational modifications.

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Although these injections are safe when administered under the supervision of a qualified medical professional, they may cause specific allergic reactions if done incorrectly
