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Male mice underwent rapid loss of survival at extended time points, while female mice were largely unaffected

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Gemcitabine Galactose-modified Gemcitabine also called senescence-specific killing compound 1 (SSK1) decreases senescent cells viability in multiple cell types, in mice and human in vitro models as well as in a broad range of inductions such as irradiation, replicative exhaustion, OIS and oxidative or genotoxic stress

doi: 10.1007/s10549-009-0594-8 11 HilvoMDenkertCLehtinenLMullerBBrockmollerSSeppanen-LaaksoTet al

10.1016/j.bbi.2015.01.008 Brain Behav