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Description
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Cvetkovic et al., 2022)
Patients typically present with reduced numbers of Faecalibacterium , Roseburia , Akkermansia , and Bifidobacterium , alongside an increased abundance of Ruminococcus , Fusobacteria , and Blautia
PPAT transfers glutamine-derived nitrogen to 5-phosphoribosyl pyrophosphate (PRPP), and this step is considered the initial step in purine biosynthesis 37
O antigen, which can be detected by complement, and receptors such as CD14 and C-type lectin-2, has far less immunostimulatory potential
