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Mechanism: A synthetic tetrapeptide that activates telomerase, the enzyme responsible for extending telomeres, thereby promoting cellular longevity and delaying aging

L. I. Fedoreyeva, I. I. Kireev, V. Kh. Khavinson, and B. F. Vanyushin, Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA, Pleiades Publishing Ltd, Nov. 2011. doi: 10.1134/s0006297911110022

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However, the GH/IGF-I axis in these disease states generally resets itself following the resolution of the inflammatory trigger (65)

Systemic delivery of peptides by the oral route: formulation and medicinal chemistry approaches