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Studies show that -synuclein may bind iron directly, promoting its aggregation, while lipid peroxidation products further stabilize toxic oligomers (Wang et al., 2023

Glutathione functions include: improving the immune system, repairing DNA, and detoxification of harmful substances such as pharmaceutical drugs, radiation, and many other toxins

Accumulation of sLG could be either due to a higher activity/abundance of GLO1 37 or lower activity/abundance of the subsequent enzyme in the pathway - GLO2 67,68

These genes are identified as GPT (also designated GPT1) and GPT2

Future studies should standardize methodological approaches across populations and increase sample sizes in order to distinguish between geographic and pathological microbiome variations