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Several ongoing prospective clinical trials are aiming to achieve comparable results, including patient-tailored therapy for colorectal peritoneal metastases (NCT06057298), sarcoma and melanoma (NCT04986748), and breast cancer (NCT05177432) 5
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Inhibiting this axis may also offer novel therapeutic avenues for EC

PMID: 32045024

the Ras/MEK/ERK pathway, and the PI3K/AKT/mTOR pathways both of which are being investigated as potential therapeutic targets (120)
