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Higher dosages of melatonin in autism spectrum disorders would be reasonable for improving disrupted melatonin rhythms rather than low-dose melatonin administration [32,33,34], considering the findings on dysfunction of circadian rhythms and attenuation of melatonin rhythm

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A sample was considered positive for neutralizing antibodies if a 1.5-fold increase in ECL signal was observed at any of the 3 concentrations of exogenous AMG 966