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CGA can facilitate cholesterol elimination by modulating homeostasis of bilirubin and bile acids via farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR) gamma coactivator 1-alpha (PGC-1) or fibroblast growth factor (FGF) 15 pathways [42,43]
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Systematic capture of dosing patterns, formulation source, route of administration, and standardized clinical outcomes may be more informative than continued reliance on heterogeneous mechanistic studies
The pharmacokinetics of Mn/TI@mHSA and P-Mn/TI@mHSA in blood circulation were investigated
