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10.1073/pnas.0914009107 80 RajaramP.SubramanianR

( K ) Fasn mRNA levels in mouse liver

Chemosensors 10 , 16 (2022)

Across human studies and reviews, adverse effects are uncommon at typical supplemental intakes, and when side effects do occur, they are usually mild and gastrointestinal in nature.12 13 44 A safety-focused review published in European Review for Medical and Pharmacological Sciences summarized available clinical and non-clinical data on myo-inositol and reported that only very high intake (around 12g per day) was consistently associated with side effects specifically mild gastrointestinal symptoms such as nausea, gas/flatulence, and diarrhea.44 The authors also noted that the severity of these effects did not increase with higher doses
doi: 10.2147/cpaa.S6262 72 GanorYBesserMBen-ZakayNUngerTLeviteM
