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Upstream molecular targets, such as Nrf2, Sirt3, and PPAR-, are responsible for the curcumin-enhanced GSH system [184186]

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Potent ingredients like vitamin C, retinoids, and exfoliating acids can sometimes conflict with copper peptides, potentially causing irritation or making them less effective

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doi: 10.1016/s0162-0134(02)00406-3 109 BoonstraJPostJA
