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B vitamins play an important role in many of the body's functions, including energy production, nerve function, cognitive function, immune system function, and the synthesis of hormones and red blood cells

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When to Adjust Dosing Increase dose if: After 4-6 weeks at current dose, no measurable body composition changes occur, youre tolerating current dose without side effects, youre below the upper clinical range (1 mg daily), and your physician approves escalation based on comprehensive assessment

It has been reported that TNF- may induce the production of IL-6 (19), IL-8 (20) and IL-10 (21)