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Description
Firstly, the issue of tolerance cannot be ignored

The cancelled Phase I trial was not buried by a regulator
This breaks down how long a typical Coremend Blend (BPC-157, KPV, TB-500) cycle runs and what research suggests happens at each stage
While no human study has demonstrated that either compound causes or accelerates cancer in research subjects, sustained pro-angiogenic signaling over long, indefinite periods is a theoretical concern around any undetected malignancy

FDA-related reports and medical reviews describe BPC-157 as an unapproved peptide with limited human evidence, so human safety remains uncertain
