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Mature erythrocytes lack nuclei and mitochondria, and are therefore incapable to generate energy via the TCA cycle

In contrast, if the pre-neoplastic lesion dose does not initiate either senescence or apoptosis, these cells continue to grow and form a malignant phenotype [195]
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Proc Natl Acad Sci USA 99:517522 Tuzet A, Rahantaniaina MS, Noctor G (2019) Analyzing the function of catalase and the ascorbateglutathione pathway in H 2 O 2 processing: insights from an experimentally constrained kinetic model
