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nine to 11 points indicate moderate DPN

Kidney Concerns at High Doses In the 2-year MS trial using 1,200 mg/day, a greater number of participants in the alpha-lipoic acid group experienced protein in the urine (proteinuria) and poor kidney function compared to placebo [19]

The oxidative stress hypothesis of Parkinson disease was investigated using a range of interventions thought to reduce cellular oxidative load, including the antiparkinsonian drug apomorphine, to investigate their effects on MPTP-induced dopamine neuron death (Grnblatt et al

Thus, achieving specificity for particular GST variants while minimizing interactions with other isoforms remains challenging due to their structural similarities

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