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Since ancient times, plant extracts from a diverse range of medicinal plants have been used in the treatment of different diseases, owing to the presence of specific PSMs
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There is an assumption that the SAR is built on interaction with the therapeutic target alone
(10) Also excluded were those who had received liver function-enhancing medications, antibiotics, choleretic agents, antioxidants, or dietary supplements within 14 days of the first dose of the investigational product, or who did not agree to abstain from such medications from 14 days to the end of the study, (11) and those who had received drugs that induce or inhibit drug metabolizing enzymes, such as barbiturates, within 30 days of the first dose of the investigational product, or who did not agree to abstain from such drugs from 30 days to the end of the study

Furthermore, when combined with immune checkpoint blockade, liproxstatin-1 displayed synergistic effects in suppressing tumor growth (112)
