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These regulate various processes in the body such as growth, digestion, immunity, and many others

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IAV has been shown to suppress SIRT2, thereby enhancing viral replication 70

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Although functional data supporting a trans- inhibition model were obtained when constitutive activation of JAK2 was shown with a JAK2 construct where the pseudokinase and KDs were swapped and this construct showed significant cytokine-independent activation only in the presence of wild-type JAK2 (51)