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Familial studies further support the role of genetic predisposition, with first-degree relatives of UC patients showing a higher risk of developing the disease

The purpose of this study was to examine the effects of glutathione supplementation on muscle fatigue in exercise as a result of improved muscular aerobic metabolism

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These inconsistent results also translate to human studies where obesity and steatosis correlated with increased hepatotoxicity after an APAP overdose in some studies [181] and no correlation of toxicity with obesity was observed in other studies [182]

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