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Yes no known interactions

That doesn't make it reckless if you're monitoring appropriately, but it does mean the risk-benefit calculation is yours to make with incomplete information

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There is growing evidence, including findings obtained in experiments using heterochronic parabiosis in mice as a model system, that age-related changes in circulating anti-geronic factors importantly contribute to the regulation of vascular aging processes and the genesis of endothelial dysfunction and oxidative stress in a noncell autonomous manner [9]

Dosing information Usual Adult Dose for Pernicious Anemia: Initial dose: 100 mcg intramuscularly or deep subcutaneous once a day for 6 to 7 days If clinical improvement and reticulocyte response is seen from the above dosing: 100 mcg every other day for 7 doses, then: 100 mcg every 3 to 4 days for 2 to 3 weeks, then: Maintenance dose: 100 to 1000 mcg monthly Duration of therapy: Life Comments: Administer concomitant folic acid if needed