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Moreover, this kind of plasticity implies that the programming of long-term outcomes might arise from brief and subtle changes in the nutritional environment during developmental stages when nutrient demands for growth are still relatively low, like the periconceptional period and early embryogenesis, rather than from significant nutritional deficits during organogenesis and differentiation

Aliment Pharmacol Ther 2010;31: 34558 [DOI] [PubMed] [Google Scholar] 7.Kheradpezhouh E, Ma L, Morphett A, Barritt GJ, Rychkov GY.TRPM2 channels mediate acetaminophen-induced liver damage

A single intragastric alcohol dose caused gastric lesions, brain swelling, intracranial hypertension, liver and kidney damage, lung injury, and severe thrombosis

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