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In summary, how to specifically inhibit the amino acid metabolism of tumor cells and immunosuppressive cells in the microenvironment, and enhance the amino acid metabolism of anti-tumor immune cells such as CD8 + T cells, is an urgent problem to be solved
any temperature excursion above 15C triggers irreversible peptide aggregation

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Endoplasmic reticulum Ca(2+) signaling and calpains mediate renal cell death

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