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In addition, inhibiting drug efflux is also a feasible antitumor strategy
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310 The discovery that some sirtuins, including mammalian SirT6 311 and Sir2A from Plasmodium falciparum (312) selectively hydrolyze long-chain acyl groups from the side chains of internal lysine residues suggests that this reaction is important enough in vivo for the evolution of protective mechanisms
Nowiski A, Ufnal M
